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糖皮质激素可用于Graves病的治疗,能够有效地降低血清总甲状腺素水平。本文观察倍他米松(betamethasone)对Graves病血清游离甲状腺素水平(FT_3和FT_4)的影响,进一步说明糖皮质激素对Graves病的治疗作用。方法38例Graves病随机分成2组,每组19例(男3例,女16例)。两组间血甲状腺素水平、甲状腺吸~(131)I率以及临床表现均无显著差异。治疗组每日口服倍他米松6mg,5天后改为每日服4.5mg共1周,然后减为每日3 mg。对照组服用安慰剂。结果治疗组于服药后5天,FT_3即已有显著性
Glucocorticoids can be used in the treatment of Graves disease, can effectively reduce the serum total thyroxine levels. This article observes the effects of betamethasone on serum free thyroxine levels (FT_3 and FT_4) in Graves ’disease and further illustrates the therapeutic effect of glucocorticoids on Graves’ disease. Methods Thirty-eight patients with Graves disease were randomly divided into two groups, 19 cases in each group (3 males and 16 females). There was no significant difference in the levels of thyroxine, thyroid suction ~ (131) I, and clinical manifestations between the two groups. The treatment group daily oral betamethasone 6mg, 5 days to 4.5mg per day for a total of 1 week, then reduced to 3 mg daily. Control group took placebo. Results The treatment group 5 days after taking FT_3 has been significant