一中毒型痢疾(以下简称毒痢)的发病机制是一直未弄清的问题,因此,在治疗上缺乏有效的办法。我们在开始研究时,根据毒痢病儿病程变化的特点,认为这病之所以凶险,其最本质的病变是在神经系统的高级生命中枢功能的紊乱,即循环及呼吸功能的改变。虽然痢疾杆菌是肠道病原菌,能引起大肠部位的病变,而毒痢则是痢疾杆菌毒素在作用于肠道前即侵犯中枢神经系统引起严重 The pathogenesis of a poisoning dysentery (hereinafter referred to as poisoning dysentery) is a problem that has not been fully understood. Therefore, there is a lack of effective treatment in the treatment. At the beginning of our study, according to the characteristics of the course of disease in children with drug-induced dysentery, the reason why the disease is so dangerous is that the most essential lesion is the disorder of central nervous system function, namely, circulatory and respiratory changes. Although dysentery bacilli are intestinal pathogens, can cause lesions of the large intestine, and toxic dysentery is Shigella toxin in the role of the gut that infringe the central nervous system caused serious