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目的探讨采用保存羊膜和新鲜羊膜治疗眼表疾病的可行性,评价其疗效。方法30例眼表疾病应用保存羊膜移植治疗,30例应用新鲜羊膜移植治疗。结果新鲜羊膜组30例羊膜均成活,保存羊膜组29例成活,1例部分溶解,部分患者视力提高。翼状胬肉复发:新鲜羊膜组1例,保存羊膜组2例。睑球粘连者结膜囊形成,眼球运动正常。持续性角膜上皮缺损伴溃疡者角膜上皮修复。结论新鲜羊膜和保存羊膜均可以有效重建眼表,降低翼状胬肉的复发率,促进角膜上皮的修复,防止睑球粘连。
Objective To investigate the feasibility of using preserved amniotic membrane and fresh amniotic membrane in the treatment of ocular surface diseases and to evaluate its curative effect. Methods 30 cases of ocular surface disease were treated with preserved amniotic membrane transplantation and 30 cases were treated with fresh amniotic membrane transplantation. Results All 30 amniotic membranes were survived in fresh amniotic membrane group, 29 in surviving amniotic membrane group survived, 1 case was partly dissolved, and some patients had increased vision. Pterygium recurrence: fresh amniotic membrane in 1 case, preserved amniotic membrane in 2 cases. Sympathetic conjunctiva sac formation, normal eye movement. Persistent corneal epithelial defect with corneal epithelial repair of ulcer. Conclusion Both fresh amniotic membrane and preserved amniotic membrane can effectively reconstruct ocular surface, reduce the recurrence rate of pterygium, promote the repair of corneal epithelium and prevent the symblepharon.