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一、引言长寿命放射性核素沉积在骨骼内,可使成骨细胞及破骨细胞由于核素特点不同而受到不同程度的照射。这种照射可以使骨组织形成恶性肿瘤,特别是骨肉瘤。已对一些核素进行了动物体内试验,包括天然放射性核素如~(226)Ra、~(228)Ra 和~(228)Th,核反应堆产生的核素如~(238)Pu、~(239)Pu、~(241)Am、~(249)Cf、~(252)Cf 和~(253)Es。动物试验及人体对亲骨核素反应的比较;主要是根据人们事故性及治疗性受到~(226)Ra 及
I. INTRODUCTION Long-lived radionuclides are deposited in the skeleton, enabling osteoblasts and osteoclasts to be exposed to different degrees due to different characteristics of the radionuclides. This irradiation can make bone tissue formation of malignant tumors, especially osteosarcoma. In vivo experiments have been performed on some of the radionuclides, including natural radionuclides such as ~ (226) Ra, ~ (228) Ra and ~ (228) Th, nuclides produced by nuclear reactors such as ~ 238 Pu, ~ 239 ) Pu, ~ (241) Am, ~ (249) Cf, ~ (252) Cf and ~ (253) Es. Animal experiments and the human body compared to the response of the pro-bone nude; mainly based on accidental and therapeutic people by ~ (226) Ra and