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目的探讨脂肪肝的影响因素,为脂肪肝预防及其临床诊断、治疗提供参考。方法分析308例脂肪肝患者的性别及年龄分布、血脂水平、肝功能、合并症等,另取100例健康查体者为对照组。结果脂肪肝患者性别比无差异,主要分布于40～60岁;非酒精性脂肪肝患者血液中TG、TC、LDL-ch水平均明显高于对照组(P<0.05或0.01);ALT升高在非酒精性脂肪肝组中明显(P<0.01),AST/ALT<1,AST升高在酒精性脂肪肝组中较为显著(P<0.01)。结论在脂肪肝病患者中,非酒精性脂肪肝病最为多见;脂肪肝与高血压、冠心病、肥胖、糖尿病等关系十分密切。
Objective To investigate the influencing factors of fatty liver and provide reference for the prevention of fatty liver and its clinical diagnosis and treatment. Methods The gender and age distribution, blood lipid level, liver function and comorbidity of 308 patients with fatty liver were analyzed. Another 100 healthy people were selected as the control group. Results There was no significant difference in the sex ratio of patients with fatty liver, which mainly distributed in 40-60 years old. The levels of TG, TC and LDL-ch in the non-alcoholic fatty liver were significantly higher than those in the control group (P <0.05 or 0.01) In non-alcoholic fatty liver group (P <0.01), AST / ALT <1, AST increased in alcoholic fatty liver group was more significant (P <0.01). Conclusion Among patients with fatty liver disease, non-alcoholic fatty liver disease is most common. Fatty liver disease is closely related to hypertension, coronary heart disease, obesity and diabetes.