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本科自1996年3月～1998年3月共收治药物性肾损害42例,其中药物滥用导致急性肾衰者10例,现总结教训以供借鉴。 1 一般资料 10例病人中男、女各5例,年龄26～63岁,平均45.3岁。用药前5例肾功异常,5例正常。 2 用药经过及转归 抗生素:3例。其中2例因“上感”予庆大霉素48万U ivgtt qd,3～5天,头孢唑啉钠4.0 ivgtt qd,5～12天。5天后因少尿发现急性肾衰,均死于急性左心功能衰竭。1例因“腹泻”予庆大霉素32万U
Undergraduate from March 1996 to March 1998 were treated 42 cases of drug-induced renal damage, including drug abuse caused acute renal failure in 10 cases, are summarized lessons for reference. 1 General Information 10 patients were male and female in 5 cases, aged 26 to 63 years, mean 45.3 years old. 5 cases of renal dysfunction before medication, 5 cases of normal. 2 after treatment and the outcome of antibiotics: 3 cases. Two cases of “upper flu” to gentamicin 48 million U ivgtt qd, 3 to 5 days, cefazolin 4.0 ivgtt qd, 5 to 12 days. Acute renal failure was found after 5 days due to oliguria and died of acute left heart failure. 1 case due to “diarrhea” to gentamicin 320,000 U.