针对尿囊素凝胶的质量标准进行研究。方法:采用安捷伦十八烷基硅烷键合硅胶色谱柱(218 mm×4.6mm,5μm),甲醇-0.02 mo.lL-1磷酸二氢钾溶液(2:98),检测波长为210nm,流速为1.0ml/min,柱温为30℃。尿囊素在16～100μg.mL-1范围内呈良好的线性关系(r=0.99996)。尿囊素平均回收率分别为99.3%。结论:本法简便、准确,可用于尿囊素凝胶的质量控制。 The allantoin gel quality standards were studied. Methods: The Agilent octadecylsilane bonded silica column (218 mm × 4.6 mm, 5 μm) was used. Methanol-0.02 mol·L-1 potassium dihydrogen phosphate solution (2:98) was used. The detection wavelength was 210 nm and the flow rate was 1.0ml / min, the column temperature is 30 ℃. Allantoin had a good linear relationship in the range of 16 ~ 100μg.mL-1 (r = 0.99996). The average recoveries of allantoin were 99.3%. Conclusion: This method is simple and accurate and can be used for the quality control of allantoin gel.