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观察增龄对小鼠淋巴因子(IL-1、IL-2)产生的影响及补肾方六味地黄汤和活血方丹坤汤的调整作用。结果表明,老年小鼠腹腔巨噬细胞产生IL-1及脾淋巴细胞产生IL-2的能力均明显下降。经补肾方和活血方治疗的两组老年小鼠IL-1、IL-2产生能力明显提高,提示补肾和化瘀治法可能是延缓免疫衰老的重要机制。
Observe the effects of aging on the production of lymphokines (IL-1, IL-2) in mice and the regulatory effects of Bushenfang Liuwei Dihuang Decoction and Huoxue Fangdankun Decoction. The results showed that the production of IL-1 in spleen lymphocytes and production of IL-2 by peritoneal macrophages in aged mice significantly decreased. The ability of IL-1 and IL-2 production in two groups of elderly mice treated with Bushenfang and Huoxue Prescription was significantly increased, suggesting that Bushen and Huayu treatment may be an important mechanism for delaying immunosenescence.