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目的 :探讨氨甲喋呤 (MTX)单次肌肉注射治疗异位妊娠的适应症、疗效及安全性。方法 :对 6 0例患者单次肌肉注射MTX5 0mg/m2 。给药后观察患者一般情况 ,定时监测血β -HCG水平和B超检查。结果 :本组资料 5 1例成功 (包括重复用药者 ) ,成功率达 85 %。结论 :患者给药前血β -HCG水平越高 ,成功率越低 ,而包块大小与疗效无明显对应关系 ,故单次肌肉注射MTX治疗异位妊娠的适应症可适当放宽。动态监测血β -HCG水平作为重复用药及剖腹探查的观察指标
Objective: To investigate the indications, efficacy and safety of methotrexate (MTX) single intramuscular injection in the treatment of ectopic pregnancy. Methods: A single intramuscular injection of MTX 50 mg / m 2 was performed on 60 patients. Observed after administration of the general situation in patients with regular monitoring of serum β -HCG levels and B-ultrasound. Results: In this group of 51 cases of successful data (including repeated medication), the success rate of 85%. CONCLUSION: The higher the level of β -HCG in patients before administration, the lower the success rate. However, there is no significant correlation between the mass and curative effect. Therefore, the indication of single intramuscular injection of MTX for ectopic pregnancy may be appropriately relaxed. Dynamic monitoring of blood β-HCG levels as repeated medication and laparotomy observation indicators