一、前言早在1816年 Stoh 首先报告了咽喉炎和风湿症的关系,1901年 Singer 报告了扁桃体疾病与风湿病之间的关系,约在同一时期 Karschm-an 提及扁桃体疾病对某些肾脏病的意义,直到1912年 Billing’s 首创病灶感染观点以后,这个问题就引起了医学界的重视,由过去完全从人体外寻找致病原因过渡到机体本身对疾病影响的研究上。基于变态反应,内分泌活动,胶元 I. INTRODUCTION As early as 1816, Stoh first reported the relationship between sore throat and rheumatism. In 1901 Singer reported the relationship between tonsil disease and rheumatism, and Karschmän at about the same time referred to tonsillar disease for some kidney disease The significance of this issue until after 1912, Billing’s first focal infection point of view, the problem has drawn the attention of the medical profession, from the past completely from outside the body looking for the cause of the transition to the body’s own impact on disease research. Based on allergic reactions, endocrine activity, collagen