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Objective To investigate the serum total IgE(tlgE) and specific IgE(slgE) to common allergens among allergic patients in Guangzhou,China.Methods 7 085 patients were examined for tlgE and slgE to 15 allergens,based on the protocols of reversed enzyme allergosorbent test and the sandwich enzyme-linked immunosorbent assay.Results 3 758(53.04%) patients tested positive for tlgE,and 4 640(65.49%) for slgE.Der pteronyssinus,Der farinae,eggs,and cow’s milk were the most common allergens leading to higher positive rates of slgE responses.Several peaks of sensitization were:Der pteronyssinus,Der farinae,and Blomia tropicalis at age 10-12;cow’s milk at age below 3;eggs at age 4-6.The mean level and positive rate of tlgE tended to increase in subjects sensitized to more allergens.Sensitization to Der pteronyssinus(OR,1.6;P<0.05),Der farinae(OR,1.5;P<0.05),Blomia tropicalis(OR,1.4;P<0.05),Blattella germanica(OR,1.5;P<0.05),cow’s milk(OR,1.3;P<0.05),and soy beans(OR,2.0;P<0.05) were independently correlated with allergy-related conditions in preliminary diagnosis.Conclusion The major allergens in Guangzhou include Der pteronyssinus,Der farinae,cow’s milk,and eggs.Sensitization to these allergens appears to be predictors of allergy-related disorder.
Objective To investigate the serum total IgE (tlgE) and specific IgE (slgE) to common allergens among allergic patients in Guangzhou, China. Methods 7 085 patients were examined for tlgE and slgE to 15 allergens, based on the protocols of the reversed enzyme allergosorbent test and the sandwich enzyme-linked immunosorbent assay. Results 3 758 (53.04%) patients tested positive for tlgE and 4 640 (65.49%) for slgE.Der pteronyssinus, Der farinae, eggs, and cow’s milk were the most common allergens leading to higher positive rates of slgE responses. Seperal peaks of sensitization were: Der pteronyssinus, Der farinae, and Blomia tropicalis at age 10-12; cow’s milk at age below 3; eggs at age 4-6. The mean level and positive rate of tlgE tended to increase in subjects sensitized to more allergens. Sensitization to Der pteronyssinus (OR, 1.6; P <0.05), Dermisinae (OR, (OR, 1.5; P <0.05), cow’s milk (OR, 1.3; P <0.05) Orrelated with allergy-related conditions in preliminary diagnosis. Confluence The major allergens in Guangzhou include Der pteronyssinus, Der farinae, cow’s milk, and eggs. Sensitization to these allergens appears to be predictors of allergy-related disorders.