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目的观察前列腺液锌(Zn)含量与C反应蛋白(CRP)检测在不同类型慢性前列腺炎(chronic prostatitis,CP)患者诊断和治疗中的临床价值。方法采用原子吸收光谱法和免疫胶体金法检测慢性细菌性前列腺炎(CBP组,n=47例)和慢性非细菌性前列腺炎(NCBP组,n=45例)患者前列腺液中Zn与CRP的含量,同时选择40例门诊正常体检者作为对照组。比较各组Zn与CRP含量的差异性。结果 CBP组和NCBP组患者前列腺液Zn含量均明显低于对照组(P<0.05);CBP组患者CRP含量明显高于对照组(P<0.05);NCBP组患者CRP含量与对照组比较差异无统计学意义(P>0.05)。结论前列腺液中Zn含量检测可协助诊断慢性前列腺炎,而CRP含量检测则可以协助区分不同类型的慢性前列腺炎疾病。
Objective To observe the clinical value of zinc content and C-reactive protein (CRP) detection in the diagnosis and treatment of patients with different types of chronic prostatitis (CP). Methods The concentrations of Zn and CRP in prostatic fluid of patients with chronic bacterial prostatitis (CBP group, n = 47) and chronic nonbacterial prostatitis (NCBP group, n = 45) were determined by atomic absorption spectrometry and immunogold assay Content, at the same time select 40 outpatient normal physical examination as a control group. The differences of Zn and CRP contents in each group were compared. Results The levels of Zn in prostatic fluid in CBP group and NCBP group were significantly lower than those in control group (P <0.05). The CRP level in CBP group was significantly higher than that in control group (P <0.05). The CRP level in NCBP group was significantly lower than that in control group Statistical significance (P> 0.05). Conclusion The detection of Zn in prostatic fluid can help diagnose chronic prostatitis, while the detection of CRP can help distinguish different types of chronic prostatitis disease.