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目的探讨微创手术对早期宫颈癌妇女保留生育功能的作用。方法选取2013年3月至2015年3月间新疆医科大学第二附属医院收治的194例早期宫颈癌患者,综合病理检测结果和患者意愿,对其中82例患者采用腹腔镜微创手术方式进行治疗,保留生育功能,设为试验组。对其余112例患者采用传统经腹宫颈癌根治方式进行治疗,设为对照组。比较两组患者围手术期相关指标及试验组术后妊娠情况。结果试验组患者中有79例成功完成保留生育功能手术,3例患者因术中冰冻切片病理检查结果不符合保留生育功能手术条件,改行腹腔镜下子宫广泛切除手术。试验组患者手术时间长于对照组,出血量、术后肛门排气时间和住院时间均低于对照组,两组比较,差异均有统计学意义(均P<0.05)。试验组患者中妊娠成功22例(27.8%),早产3例(3.8%),流产7例(8.9%),成功分娩12例(15.2%)。结论早期宫颈癌妇女接受微创保留生育功能手术损伤小,术后恢复较快,出血量较少,且能有效改善术后妊娠结局,具有一定的临床价值。
Objective To explore the role of minimally invasive surgery in preserving reproductive function in women with early cervical cancer. Methods A total of 194 early cervical cancer patients admitted to the Second Affiliated Hospital of Xinjiang Medical University from March 2013 to March 2015 were selected and 82 cases were treated by laparoscopic minimally invasive surgery , Retain fertility function, as the experimental group. The remaining 112 patients with traditional radical cesarean cervical cancer treatment, as the control group. Perioperative indexes and postoperative pregnancy in the two groups were compared. Results In the experimental group, 79 patients successfully completed the fertility preserving surgery and 3 patients underwent the laparoscopic extensive uterine resection due to the intraoperative frozen section biopsy results that did not meet the reproductive function preserving conditions. The operation time of the experimental group was longer than that of the control group. The amount of bleeding, postoperative anal exhaust time and hospital stay were lower than the control group. There was significant difference between the two groups (P <0.05). Pregnancy was successful in 22 patients (27.8%), premature delivery in 3 patients (3.8%), abortion in 7 patients (8.9%), and successful delivery in 12 patients (15.2%) in the test group. Conclusion Early cervical cancer women with minimally invasive surgery have the advantages of less invasive surgery, faster postoperative recovery, less bleeding, and can effectively improve the outcome of postoperative pregnancy, which has certain clinical value.