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有关醋酸棉酚抑制实验动物精子发生和作为男用避孕药进行临床试验研究已有过不少报告。已知棉酚可破坏大鼠的精子及精子细胞,临床健康人每日服20毫克醋酸棉酚,连服50天可使精子数降到400万/每毫升以下。毒付作用不明显,避孕效果可靠。但棉酚对人睾丸曲细精管生精上皮的作用过程、环节及破坏程度是否也和大鼠一样,尚未进行过细致的研究。本研究的目的是试图通过对服药后人精液中脱落细胞的动态观察,分析
There have been many reports about the inhibition of acetic acid gossypol on experimental animal spermatogenesis and clinical trials as male contraceptives. Known gossypol can damage rat sperm and sperm cells, clinical healthy people daily dose of 20 mg gossypol acetate, even serving 50 days can sperm count down to 4000000 / per ml below. Drug poisoning effect is not obvious, contraceptive effect is reliable. However, gossypol on human testicular seminiferous epithelium of seminiferous epithelium of the role of the process, the extent and extent of damage is also the same as in rats, has not been carefully studied. The purpose of this study is to try to analyze the dynamics of exfoliated cells in human semen after taking the drug