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目的探讨新净界(复合溶葡萄球菌酶)在慢性阻塞性肺疾病(COPD)患者发生口腔真菌感染中的治疗意义。方法 100例发生口腔真菌感染的COPD患者随机分为对照组和治疗组,各50例,在其他治疗方案相同的条件下对照组予以制霉菌素凝胶涂抹口腔(2次/d),治疗组给予新净界喷涂口腔,治疗7 d后比较两组患者口腔真菌感染的治疗效果。结果对照组显效率为76%治疗组显效率为75%,两组显效率差异无统计学意义(P>0.05)。结论新净界对于发生口腔真菌感染的COPD患者有临床疗效且对人体无不良反应,可以临床推广使用。
Objective To investigate the therapeutic effect of neojiejie (complex lysostaphin) on oral fungal infection in patients with chronic obstructive pulmonary disease (COPD). Methods 100 cases of COPD patients with oral fungal infection were randomly divided into the control group and the treatment group, 50 cases in each group. The control group was treated with nystatin gel orally (2 times / d) under the same treatment conditions. The treatment group New net boundary spray was given to the oral cavity, and the treatment effect of oral fungal infection was compared between the two groups after 7 days of treatment. Results The effective rate of the control group was 76%, the effective rate of the treatment group was 75%, there was no significant difference between the two groups (P> 0.05). Conclusion The new net boundary for the occurrence of oral fungal infection COPD patients with clinical efficacy and no adverse reactions to the human body, can be used clinically.