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目的观察高聚生联合顺铂治疗恶性胸水的疗效及毒性。方法将46例恶性胸水患者随机分为两组,治疗组24例予高聚生加顺铂治疗,对照组22例单予顺铂治疗进行比较。结果治疗组有效率高于对照组,Karnofsky评分高于对照组,且不良反应少于对照组。结论高聚生联合顺铂治疗恶性胸水疗效确切,能有效控制胸水,提高生存质量,减少毒副反应。
Objective To observe the efficacy and toxicity of hypercoagulation combined with cisplatin in the treatment of malignant pleural effusion. Methods Forty-six patients with malignant pleural effusion were randomly divided into two groups. 24 cases in the treatment group were given hyperbranched plus cisplatin, and 22 cases in the control group were treated with cisplatin alone. Results The treatment group was more effective than the control group, Karnofsky score higher than the control group, and adverse reactions less than the control group. Conclusions High polyaddition combined with cisplatin in the treatment of malignant pleural effusion is effective, which can effectively control pleural effusion, improve quality of life and reduce side effects.