我院１９８３～１９９２年共施行肾移植４５例，应用常规免疫抑制剂３例，应用ＣＳＡ三联用药４２例，后者效果明显优于前者，急性排异率减少到４０％，症状减轻，逆转容易，感染率降至２１．４％，人肾一年存活率提高到９１．４％。本文报道１３例病人测定ＣＳＡ谷值的作用及应用心痛定是预防肾毒性的有效性。 Our hospital from 1983 to 1992, 45 cases of renal transplantation were performed, the application of conventional immunosuppressive agents in 3 cases, the application of CSA triple therapy in 42 cases, the latter was significantly better than the former, the acute rejection rate reduced to 40%, reduce the symptoms and reverse easily , The infection rate dropped to 21.4% and the one-year survival rate of human kidney increased to 91.4%. This article reports the 13 patients in the determination of the value of CSA Valley and the application of nifedipine is to prevent the effectiveness of nephrotoxicity.