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目的观察慢性消化道溃疡联合用药治疗的效果。方法根据研究要求,以随机的方式抽取86例患者参与研究,并将其均分成两组,即对照组43例和观察组43例,病例到院治疗时间为2013年5月至2015年7月,两组患者在治疗期间均禁止食用过冷、辛辣刺激性食物,戒烟限酒,对照组使用奥美拉唑、阿莫西林、克拉霉素、胶态果胶铋治疗,观察组基于此加用中药治疗,观察分析两组患者治疗效果、幽门螺杆菌转阴情况以及随访3个月期间复发情况,并进行比较。结果经治疗,观察组治疗总有效率为95.35%,幽门螺杆菌转阴率为93.02%,复发率为6.98%;对照组治疗总有效率为76.74%,幽门螺杆菌转阴率为67.77%,复发率为25.58%,二者数据经比较差异有统计学意义(P<0.05)。结论在慢性消化道溃疡的临床中,采取联合用药的方式进行治疗,效果好,值得应用于临床和进一步推广。
Objective To observe the effect of combined treatment of chronic peptic ulcer. Methods According to the research requirements, 86 patients were randomized to participate in the study and divided into two groups, 43 cases in the control group and 43 cases in the observation group. The treatment time from hospital arrival to hospital was from May 2013 to July 2015 , Two groups of patients were prohibited during treatment were eating cold, spicy food, smoking and alcohol restriction, the control group using omeprazole, amoxicillin, clarithromycin, colloidal bismuth colloidal treatment group observation based on this plus Treatment with traditional Chinese medicine, observation and analysis of two groups of patients with treatment, Helicobacter pylori negative situation and follow-up of 3 months recurrence, and compared. Results After treatment, the total effective rate was 95.35% in the observation group, 93.02% in the H.pylori group, and the recurrence rate was 6.98%. The total effective rate in the control group was 76.74%, the negative conversion rate in Helicobacter pylori was 67.77% The recurrence rate was 25.58%, the difference between the two data was statistically significant (P <0.05). Conclusions In the clinical treatment of chronic peptic ulcer, taking combination therapy is effective and should be applied to clinical and further promotion.