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目的探讨原发性腹膜后神经鞘瘤的临床诊断、治疗、病理特征及预后。方法回顾性分析2000年1月至2011年12月我院外科治疗的3例原发性腹膜后神经鞘瘤患者的临床资料,并复习相关文献,综合分析腹膜后神经鞘瘤的诊断及治疗。结果 3例均行手术治疗,均为完整切除,病理证实为腹膜后神经鞘瘤,术后随访半年至2年无复发。结论腹膜后神经鞘瘤临床罕见,缺乏临床特异性,绝大部分为良性,术前诊断困难,确诊依靠病理组织学及免疫组化检查。主要治疗方法为手术治疗。良性神经鞘瘤预后良好,恶性神经鞘瘤对放化疗不敏感,预后差。
Objective To investigate the clinical diagnosis, treatment, pathological features and prognosis of primary retroperitoneal schwannoma. Methods The clinical data of 3 patients with primary retroperitoneal schwannoma surgically treated in our hospital from January 2000 to December 2011 were analyzed retrospectively. The related literatures were reviewed, and the diagnosis and treatment of retroperitoneal schwannoma were comprehensively analyzed. Results All the 3 cases underwent surgical resection, all of which were completely resected. The pathological findings were retroperitoneal schwannoma. No recurrence was observed after 6 months to 2 years follow-up. Conclusions Retroperitoneal schwannoma is clinically rare and lacks clinical specificity. Most of them are benign and difficult to diagnose before operation. Diagnosis depends on histopathology and immunohistochemistry. The main treatment for surgery. Benign schwannoma prognosis is good, malignant schwannoma is not sensitive to radiotherapy and chemotherapy, the prognosis is poor.