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勃起功能障碍(ED)与男性高血压有着较高的并存率,且高血压患者往往同时服用多种抗高血压药物,治疗ED的一线口服药西地那非对此类患者的效果和安全性如何呢?Albuquerque DC等人进行的相关研究给了我们一些启示。共有来自巴西7个研究中心的联用2种以上抗高血压药物的120名高血压患者入选,年龄30～81岁,ED病程6个月以上。患者随机接受西地那非或安慰剂治疗,初始剂量为50mg,可调节至25mg或100mg,性交前1h服药。8周后评估生命体征、副作用、疗效及满意度,并记
Erectile dysfunction (ED) and male hypertension have a high coexistence rate, and hypertension patients often take multiple antihypertensive drugs at the same time, the treatment of ED first-line oral administration of sildenafil in such patients with the effect and safety How? Albuquerque DC, who conducted some relevant research gives us some inspiration. A total of 120 hypertensive patients with two or more antihypertensive drugs from seven research centers in Brazil were enrolled. Their ages ranged from 30 to 81 years and the duration of ED was over 6 months. Patients randomized to sildenafil or placebo treatment, the initial dose of 50mg, can be adjusted to 25mg or 100mg, 1h before sexual intercourse medication. Eight weeks later, vital signs, side effects, efficacy and satisfaction were assessed and recorded