【摘 要】
：
目的 探讨肥胖少年的臂-踝脉搏波速度(brachial-ankle pulse wave velocity,BaPWV),与诱发心血管疾病发生的血生化指标的相关性.方法 在北京市海淀区选取165例14～17岁的肥胖少年,男90例,女75例,测量体重、身高、血压后,计算BMI,采用动脉硬化检测仪测量臂-踝脉搏波速度(BaPWV),同时检测空腹血生化指标.分析BaPWV与肥胖相关指标,以及心血管疾病危险因素中血生化指标的关系.结果 过度肥胖组的BaPWV,与总胆固醇(total cholesterol,TC)
【机 构】
：
北京市海淀医院,儿科,北京 100080;北京市海淀医院,检验科,北京 100080;北京市海淀医院,体检中心,北京 100080
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目的 探讨肥胖少年的臂-踝脉搏波速度(brachial-ankle pulse wave velocity,BaPWV),与诱发心血管疾病发生的血生化指标的相关性.方法 在北京市海淀区选取165例14～17岁的肥胖少年,男90例,女75例,测量体重、身高、血压后,计算BMI,采用动脉硬化检测仪测量臂-踝脉搏波速度(BaPWV),同时检测空腹血生化指标.分析BaPWV与肥胖相关指标,以及心血管疾病危险因素中血生化指标的关系.结果 过度肥胖组的BaPWV,与总胆固醇(total cholesterol,TC)、低密度胆固醇(low density lipoprotein cholesterol,LDL-C)、三酰甘油(triglyceride,TG)呈正相关关系;与体重、体质指数(body mass index,BMI)、收缩压呈正相关关系.按照BaPWV测量值分组,BaPWV增高组(高于正常范围,>P95)的BaPWV,与总胆固醇(TC)、低密度胆固醇(LDL-C)呈正相关关系;与年龄、体重、体重指数(BMI)呈正相关关系.BaPWV增高与暴露于过度肥胖(BMI>P50)之间关联强度的比值比OR=2.159,OR的95％可信区间为1.011～4.613.说明过度肥胖会使BaPWV高于正常范围(>P95)的危险度增加2.159倍.结论 总胆固醇(TC)和低密度胆固醇(LDL-C),与过度肥胖(BMI>P50),以及BaPWV高于正常范围(>P95)有正相关性.过度肥胖会使BaPWV高于正常范围(>P95)的危险度增加.
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