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目的了解美施康啶的镇痛效果,为临床合理用药提供依据。运用美施康定的缓释持续镇痛的作用,达到满意的止痛效果。方法采用开放式无对照法,对本院肿瘤科114例使用美施康定治疗的中晚期癌症患者镇痛效果进行系统观察,并进行分析。结果美施康定的日剂量在30~300mg之间,大多数患者均可获得良好的止痛效果,治疗后疼痛全部有所缓解,有效率为98·2%,不良反应为便秘、恶心、呕吐、头昏、嗜睡、排尿困难,未见其他严重的药物不良反应。结论美施康定是中、晚期癌症患者可以长期使用且安全性高的重要止痛药物之一。
Objective To understand the analgesic effect of mesyconazole and provide basis for clinical rational drug use. The use of sustained-release mesyconazole sustained analgesic effect, to achieve satisfactory analgesic effect. Methods The open-label, uncontrolled method was used to systematically observe the analgesic effect of 114 cases of advanced cancer patients treated with Meishi Kangding in our hospital oncology department. Results The daily dose of Meishi Kangding between 30 ~ 300mg, most patients can get good analgesic effect after treatment, all the pain relief, the effective rate was 98.2%, adverse reactions of constipation, nausea, vomiting, Dizziness, drowsiness, dysuria, no other serious adverse drug reactions. Conclusion Meishi Kangding is one of the important analgesic drugs that can be used for a long time and with high safety in patients with advanced cancer.