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为探讨肝功能异常对肾移植患者存活的影响，对４８例肾移植前后发生肝功能异常的病例资料进行分析。术前乙型肝炎病毒表面抗原（ＨＢｓＡｇ）阳性，伴或不伴丙氨酸转氨酶（ＡＬＴ）升高者３２例，术后肝功能正常者１８例，肝功能异常但经治疗预后好者６例，预后差者８例；术前仅ＡＬＴ升高者９例，术后肝功能正常者３例，肝功能异常但经治疗预后好者５例，预后差者１例；术前肝功能正常，术后发生肝功能异常者２８例，大部分系药物的肝毒性所致，经治疗预后好者１４例，预后差者１４例。认为ＨＢｓＡｇ阳性和ＡＬＴ异常并非肾移植术的禁忌证；对药物的肝毒性应引起足够的重视。
To investigate the effect of abnormal liver function on the survival of renal transplant recipients, 48 cases of liver dysfunction before and after renal transplantation were analyzed. Preoperative positive of hepatitis B virus surface antigen (HBsAg), with or without elevated alanine aminotransferase (ALT) were 32 cases, 18 cases of normal liver function, liver dysfunction, but the treatment of good prognosis in 6 cases , 8 patients with poor prognosis; preoperative ALT elevated in 9 cases, 3 cases of normal liver function after surgery, liver dysfunction but the treatment of good prognosis in 5 cases, poor prognosis in 1 case; preoperative liver function was normal, Postoperative liver dysfunction in 28 cases, most of the drugs caused by liver toxicity, after treatment of good prognosis in 14 cases, 14 cases of poor prognosis. That HBsAg-positive and ALT abnormalities is not a contraindication for renal transplantation; drug hepatotoxicity should cause enough attention.