愈来愈多的资料表明,隔肌疲劳在呼吸衰竭的发生机理中有重要意义,它是导致高碳酸血症呼吸衰竭的重要原因之一。因此,膈肌疲劳的治疗就显得非常重要。本文对膈肌疲劳的治疗药物包括正性肌力药物、活性氧类清除剂、参麦注射液、磷酸二酯酶抑制剂、一氧化氮合酶抑制剂等进行了综述,并对它们的作用机理进行了简要介绍。 More and more data show that the diaphragm muscle fatigue in the pathogenesis of respiratory failure is important, it is one of the major causes of hypercapnia respiratory failure. Therefore, the treatment of diaphragmatic fatigue is very important. In this paper, the treatment of diaphragmatic fatigue, including inotropic drugs, reactive oxygen species scavenger, Shenmai injection, phosphodiesterase inhibitors, nitric oxide synthase inhibitors are reviewed, and their mechanism of action A brief introduction.