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目的分析放射治疗与顺铂 (DDP)、氟尿嘧啶 (5 -Fu)、甲酰四氢叶酸钙 (CF)在放疗前后化疗对中晚期食管癌的临床疗效。方法 87例中晚期食管癌随机分为两组。放化疗组放疗前用DDP、5 -Fu、CF化疗 ,放疗后再给予 2个疗程的化疗。另一组为单纯放疗组。治疗后分别进行 1、2、3年生存率比较。结果放化疗组 1、2、3年生存率明显高于单纯放疗组。结论中晚期食管癌经化疗及放疗后生存率及生活质量明显优于单纯放化疗。
Objective To analyze the clinical effects of radiotherapy and chemotherapy of cisplatin (DDP), fluorouracil (5 -Fu) and leucovorin (CF) on advanced esophageal cancer before and after radiotherapy. Methods 87 cases of advanced esophageal cancer were randomly divided into two groups. Radiotherapy before radiotherapy with DDP, 5-Fu, CF chemotherapy, radiotherapy and then given two courses of chemotherapy. The other group was radiotherapy alone. After treatment, respectively, 1, 2, 3-year survival rate comparison. Results The 1, 2, 3-year survival rate of radiotherapy and chemotherapy group was significantly higher than that of radiotherapy alone group. Conclusions The survival rate and quality of life of patients with advanced esophageal cancer after chemotherapy and radiotherapy are obviously superior to radiotherapy and chemotherapy alone.