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近年来发现不产生激素的的上皮性卵巢肿瘤和皮样囊肿中也有产生雌激素等甾体激素的肿瘤,如果这被确定,甾体激素合成机理等的细胞生物学的意义将增加,也可期待作为肿瘤标记在临床运用。作者以不属于产生激素肿瘤范围的各种上皮性肿瘤和皮样囊肿为对象,研究其雌激素产生功能。测定卵巢肿瘤患者术前、术后末梢血中E_2值,分析阴道细胞涂片和子宫内膜组织相。研究结果:①绝经后16例术前血清E_2值平均为230.9±248.5pg/ml,与同龄组对照(12.3±3.6pg/ml)比较,显著高值(P<0.01),此外
In recent years, it has been found that epithelial ovarian tumors and dermoid cysts producing no hormones also produce tumors of estrogen and other steroid hormones. If this is confirmed, the significance of cell biology such as the steroid hormone synthesis mechanism may increase Expect to be used as a tumor marker in clinical practice. The authors study the estrogen-producing function of various epithelial tumors and dermoid cysts that do not belong to the range of hormone-producing tumors. The value of E_2 in peripheral blood of ovarian cancer patients before and after surgery was measured, and the vaginal smears and endometrial tissues were analyzed. Results: ① Preoperative serum E_2 values of 16 preoperative menopausal women were 230.9 ± 248.5pg / ml, which were significantly higher than those in the same age group (12.3 ± 3.6pg / ml) (P <0.01). In addition,