患者张某,女,40岁,主因发冷发热3天,加重伴尿少1天于94年3月7日急诊入院。入院前3天受凉后出现发冷发热,全身不适,在当地应用抗病毒,解热药物治疗未奏效。入院前1天静脉滴注10％葡萄糖500ml加庆大霉素0.64g后出现少尿,12小时尿量<100ml,并伴头晕,恶心呕吐。既往体健,无肾脏及神经病史。体检:T39℃、P120次/分、R36次/分、Bp16/10KPa、神志清楚、颜面部及双眼睑轻度浮肿,咽部轻度充血、颈软、胸称、两肺呼吸音清晰,心率120次/分,律齐,各瓣膜听诊区未闻及杂音,腹部平坦、肝 Patient Zhang, female, 40 years old, mainly due to chills and fever for 3 days, with aggravating less 1 day in March 7, 94 emergency admission. 3 days before admission, chills and fever appeared after the cold, general malaise, anti-virus in the local application, antipyretic drug treatment did not work. One day before admission, intravenous infusion of 10% glucose 500ml plus gentamicin 0.64g oliguria, 12-hour urine output <100ml, and with dizziness, nausea and vomiting. Past physical health, no history of kidney and neuropathy. Physical examination: T39 ℃, P120 beats / min, R36 beats / min, Bp16 / 10KPa, conscious, facial and double eyelid mild edema, mild pharyngeal hyperemia, neck soft, chest, lungs breath sounds clear, heart rate 120 times / min, law Qi, the valve auscultation area did not smell and noise, flat belly, liver