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背景:阿司匹林和他汀类药物都可用于冠心病(CHD)的一级预防,但联合使用二者的作用还未被研究过。目的:研究阿司匹林、他汀类药物和联合使用这两种药物及不使用药物对于男性冠心病事件一级预防的成本-效用分析。设计:采用Markov模型。数据来源:已发表的文献。目标人群:中年男性,
BACKGROUND: Aspirin and statins are used for primary prevention of coronary heart disease (CHD), but the combined effects of both have not been studied. OBJECTIVE: To study cost-effectiveness analysis of primary prevention of coronary heart disease (CHD) in men with aspirin, statins and combination of these two drugs and no drug. Design: using Markov model. Source: published literature. Target population: middle-aged men,