目的：观察地塞米松在烧伤早期创面的抗炎作用。方法：烧伤后１～２０ｈ的病人共７８例（男性５５例，女性２３例，年龄３０±ｓ１０ａ），１６６个创面，分为２组：治疗组４０例，８６个创面，用地塞米松（０．０５ｍｇ／ｍＬ）和庆大霉素（８００Ｕ／ｍＬ）混合液浸单层纱布外敷；对照组３８例，８０个创面，单用同上浓度的庆大霉素液纱布外敷。均用包扎疗法。结果：对减少渗出、水泡和肿胀的疗效，治疗组优于对照组，对浅度烧伤的愈合时间，治疗组快于对照组（Ｐ＜０．０１）。２组均未见副作用。结论：地塞米松对烧伤早期创面有较好疗效。 Objective: To observe the anti-inflammatory effect of dexamethasone in the early burn wounds. Methods: A total of 78 patients (55 males, 23 females, age 30 ± s10a) and 166 wounds were enrolled in this study. The wounds were divided into two groups: 40 cases in the treatment group and 86 cases with dexamethasone (0 .05mg / mL) and gentamicin (800U / mL) were impregnated with single layer of gauze. The control group consisted of 38 cases and 80 wounds with the same concentration of gentamicin gauze. Are using bandaging therapy. Results: The curative effect of reducing exudation, blistering and swelling was better in the treatment group than in the control group, and healing time of the shallow burn group was faster in the treatment group than in the control group (P <0.01). 2 groups were no side effects. Conclusion: Dexamethasone has a good effect on early burn wounds.