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目的了解克拉玛依市人群麻疹、风疹抗体水平,有针对性地开展麻疹、风疹免疫预防工作,有效控制麻疹、风疹的发生和流行,实现消除麻疹的目标。方法按照分层随机抽样方法,采集0~60岁健康人群1 056人份血样,采用ELISA方法,定量检测麻疹抗体、风疹抗体。结果人群麻疹抗体阳性率97.54%、风疹抗体阳性率87.22%,抗体几何平均浓度(Geometric Mean Concentration,GMC)麻疹、风疹分别为:1 220.10 m IU/ml、68.23 IU/ml,不同人群麻疹、风疹抗体阳性率差异均有统计学意义(麻疹χ~2=20.170,风疹χ~2=17.090,P均<0.05);不同地区麻疹抗体阳性率在95%以上、保护率在65%~75%之间,风疹抗体阳性率在75%~94%之间,不同地区风疹抗体阳性率差异有统计学意义(χ~2=31.106;P<0.001);不同免疫史风疹抗体阳性水平差异有统计学意义(χ~2=30.254,P<0.001)。结论克拉玛依市麻疹人群抗体阳性率总体保持在较高水平,风疹抗体阳性率水平略低,乌尔禾区和部分年龄组风疹阳性率较低。应重点加强地区及重点人群疫苗预防接种管理,必要时开展人群查漏补种免疫。
Objective To understand the level of measles and rubella in Karamay population and to carry out measles and rubella immunity prevention in a targeted manner to effectively control the occurrence and prevalence of measles and rubella so as to achieve the goal of eliminating measles. Methods According to stratified random sampling method, 1 056 blood samples were collected from healthy population aged 0-60 years. The measles antibody and rubella antibody were detected quantitatively by ELISA. Results The positive rate of measles antibody in the population was 97.54%, and the positive rate of rubella antibody was 87.22%. The Geometric Mean Concentration (GMC) measles and rubella were respectively 1 220.10 m IU / ml and 68.23 IU / ml, The positive rates of measles antibody in different areas were above 95% and the protective rates were between 65% and 75% (measles χ ~ 2 = 20.170, rubella χ ~ 2 = 17.090, P <0.05) , The positive rate of rubella antibody was between 75% and 94%, the positive rate of rubella antibody in different regions was statistically different (χ ~ 2 = 31.106; P <0.001); the positive rate of rubella antibody in different immunization history was statistically significant (χ ~ 2 = 30.254, P <0.001). Conclusion The prevalence of measles antibody in Karamay population remains relatively high, the positive rate of rubella antibody is slightly lower, and the positive rate of rubella in some areas and age groups is lower. Should focus on strengthening the vaccination of vaccines in areas and key populations, if necessary, carry out population leak vaccination.