美《医学论坛报》第22卷第6期(1981年)报道:杂合子家族性高胆固醇血症病人,因低密度脂蛋白水平升高,经传统饮食治疗和药物治疗无效,处于冠心病高度危险者,用胆酸多价螯合作用剂降胆宁(Colestipot)合并菸酸治疗,可望痊愈。旧金山大学凯恩(John Kane)医生报告60例病人的试用结果。降胆宁与菸酸合用使原为350毫克/分升的平均胆固醇值降低45％,比单用降胆宁降低20％的数值高 The United States, “Medical Tribune,” Volume 22, No. 6 (1981) reported: heterozygous familial hypercholesterolemia patients, due to elevated levels of low-density lipoprotein, the traditional diet and drug treatment ineffective, at coronary heart disease Dangerous, with cholic acid sequestrants cohoshin (Colestipot) combined niacin treatment, is expected to recover. Dr. John Kane from the University of San Francisco reported the trial results of 60 patients. Cholemai Ning combined with nicotinic acid so that the original 350 mg / dl average cholesterol value decreased by 45%, compared with the single use of cholestya to reduce the value of 20% high