醛固酮(aldosterone)是一种具有效能的肾上腺皮质激素,在新近基础生理学的重要发展中,证明是一种维持电解质与水平衡的主要因素,在疾病中,机体因这种激素作用,发生生理反应而产生并维持水肿,其意义已受到了重视.能反抗醛固酮作用的药剂,对于因此种激素生产过多而发生的水肿和其他病征,提供了新的控制作用. Cella和Kagawa氏新近提出了一系列的新的类 Aldosterone, a potent adrenocorticotropic hormone, has been shown to be a major factor in the maintenance of electrolyte-water balance in important recent developments in basic physiology, where the body undergoes a physiological response to this hormonal effect And the importance of generating and maintaining edema has been taken seriously.The agents that can counteract the effects of aldosterone provide new control over the edema and other symptoms that result from the overproduction of hormones.Clala and Kagawa recently proposed a Series of new classes