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中药糖衣片在贮存过程中有些品种出现片子边缘或其它位置开裂,常称为龟裂。本文探讨了糖衣片龟裂的原因和解决办法。我们将已龟裂和未龟裂的复方川贝精片分别做水份测定,结果表明:已裂者为7.8％,未裂者6.8％,前者含水率明显高于后者。我们认为吸湿是引起片子龟裂的一个主要原因。为此,对本厂生产的11种糖衣片做了吸湿实验,结果见附表。从表中看到:全浸膏片不发生龟裂,但片面有浸出物渗出,外表变黑。由生药粉与浸膏组成的半浸膏片均发生裂片。
Sugar-coated tablets of traditional Chinese medicine appear to have cracks on the edge of the sheet or other places during storage, and are often referred to as cracks. This article explores the causes and solutions for cracking of sugar-coated tablets. We measured the cracked and uncracked compound Chuanbeijing tablets as water content. The results showed that 7.8% of those who had cracked and 6.8% of those who had not cracked, and the moisture content of the former was significantly higher than that of the latter. We believe that moisture absorption is a major cause of film cracking. For this purpose, moisture absorption experiments were performed on 11 kinds of sugar-coated tablets produced by the factory. The results are shown in the attached table. From the table, it can be seen that cracks do not occur in the whole extract sheet, but the leachate on the sheet surface seeps out and the appearance becomes black. The semi-paste sheet consisting of crude drug powder and extract has a splinter.