口腔扁平苔藓是一种以慢性炎症状态出现在口腔粘膜上的非感染性疾病。国内外近来报告其癌变率可达0.5～10％,尤其对糜烂型扁平苔藓出现增殖、或基底变硬、失去正常柔性的情况时更要注意。我科曾在一年内遇到2例因扁平苔藓恶变成颊癌病例,故认为对糜烂型扁平苔藓更应积极治疗。该病常用的氯喹、次水杨酸铋剂、考的松类药物副作用大,疗效差。我科从1976年起采用冷冻、激光、肤轻松软膏涂擦治疗。今将观察 Oral lichen planus is a non-infectious disease that occurs in the oral mucosa in chronic inflammatory conditions. Recently reported at home and abroad its cancer rate of up to 0.5 to 10%, especially in the proliferation of erosive lichen planus appears, or the substrate hardens, the loss of normal flexibility even more attention. My department had encountered in 2 cases of lichen planus due to malignant transformation into cheek cancer cases, it is more aggressive treatment of erosive lichen planus. Chloroquine commonly used in the disease, sub salicylic acid bismuth agents, test side effects of pineal drugs, poor efficacy. Our department since 1976 using frozen, laser, skin soft ointment rubbed treatment. This will be observed