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目的观察甘精胰岛素联合阿卡波糖治疗老年2型糖尿病的疗效及安全性。方法选择我院收治的60例老年2型糖尿病患者,随机分为2组,对照组每日早晚餐前30min皮下注射预混胰岛素,治疗组采用甘精胰岛素联合阿卡波糖治疗,观察治疗后两组血糖达标的时间、胰岛素日用量、低血糖发生率。结果治疗后,两组空腹及餐后血糖均较前明显下降,治疗组胰岛素日用量、低血糖发生率均显著低于对照组(P<0.05)。结论甘精胰岛素联合阿卡波糖治疗老年2型糖尿病疗效显著,低血糖发生率低。
Objective To observe the efficacy and safety of insulin glargine combined with acarbose in the treatment of type 2 diabetes in the elderly. Methods Sixty elder patients with type 2 diabetes mellitus admitted to our hospital were randomly divided into two groups. The control group was injected with premixed insulin subcutaneously daily 30 minutes before and after meals. The patients in the treatment group were treated with insulin glargine combined with acarbose. After treatment, Two groups of blood glucose compliance time, daily insulin dosage, the incidence of hypoglycemia. Results After treatment, the fasting and postprandial blood glucose of the two groups were significantly lower than before. The daily dosage of insulin and the incidence of hypoglycemia in the treatment group were significantly lower than those in the control group (P <0.05). Conclusion Glargine and acarbose treatment of elderly with type 2 diabetes significant effect, low incidence of hypoglycemia.