反义基因治疗(antisensegenetherapy)即利用反义核酸与其靶基因或基因产物互补形成一种特殊的“基因封条结构,在转录或翻译水平阻断靶基因的异常表达,促进细胞正常分化或诱导细胞凋亡,以达到治疗肿瘤的目的。反义核酸所针对的靶点应该是在肿瘤发生中起关键作用的一种或几种癌基 Antisense gene therapy (antisensegenetherapy) is the use of antisense nucleic acid and its target gene or gene product complementarity to form a special "gene seal structure, at the transcriptional or translational level to block the abnormal expression of target genes, promote normal cell differentiation or induction of apoptosis Death in order to achieve the purpose of the treatment of cancer antisense target nucleic acid should be the key role in tumorigenesis of one or several cancer-based