分析和研究强直性脊柱炎的临床Ｘ线检查诊断方法，Ｘ线分级、分期的表现及在诊断中的重要性。方法：对８０例强直性脊柱炎患者进行Ｘ线摄片分级、分期，结合血沉（ＥＳＲ）、Ｃ－反应蛋白（ＣＲＰ）和ＨＬＡ－Ｂ_２７检查诊断。并进行统计学分析。结果： ９０％患者ＨＬＡ－Ｂ_(２７)阳性， ６０％血沉增快，骶骼关节和髓关节片以Ⅱ级改变为主，腰椎病变以早、中期Ｘ线病变者较多。结论强直性脊柱炎以青壮年男性为多见， ＨＬＡ－Ｂ_(２７)阳性率高和ＥＳＲ增快可作为Ｘ线诊断时的参考条件。Ｘ线摄片是一种简便首选的检查诊断方法，准确可靠。 To analyze and study the clinical X-ray diagnosis and diagnosis of ankylosing spondylitis, X-ray classification, staging and the importance of diagnosis. Methods: Eighty patients with ankylosing spondylitis were diagnosed by radiography, staging, combined with ESR, CRP and HLA-B27. And statistical analysis. Results: 90% of patients had positive HLA-B27, 60% erythrocyte sedimentation rate, grade Ⅱ change of sacro-joint and medullary synovial membrane. There were more X-ray lesions in lumbar lesions in early and mid-term. Conclusion Ankylosing spondylitis is more common in young and middle-aged males. The high positive rate of HLA-B 27 and the rapid ESR may be the reference conditions for X-ray diagnosis. X-ray is a simple and convenient method of examination and diagnosis, accurate and reliable.