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目的:探讨缺血修饰白蛋白(IMA)与超敏C反应蛋白(hs-CRP)在急性冠脉综合征(ACS)早期诊断中的意义。方法:使用全自动生化分析仪对206例ACS患者血清IMA和hs-CRP进行分时检测,对检测结果进行统计学分析。结果:ACS患者IMA、hs-CRP在整个监测时程内均不同程度增高,以急性心梗增高最为显著,心梗组IMA和hs-CRP的曲线下面积(AUC)分别为0.943和0.811。结论:IMA和hs-CRP对ACS尤其是急性心梗早期诊断具有较高应用价值,二者呈正相关。
Objective: To investigate the significance of IMA and hs-CRP in the early diagnosis of acute coronary syndrome (ACS). Methods: Serum IMA and hs-CRP in 206 patients with ACS were tested by time-sharing with automatic biochemical analyzer. The results were statistically analyzed. Results: The IMA and hs-CRP in ACS patients increased to different extents during the whole monitoring period. The most significant increase was acute myocardial infarction. The area under curve (AUC) of IMA and hs-CRP in MI group was 0.943 and 0.811 respectively. Conclusion: IMA and hs-CRP are of high value in the early diagnosis of acute myocardial infarction, especially in acute myocardial infarction.