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对459份肾移植前透析患者随机血清进行了抗体水平调查,对其中的72份淋巴细胞毒高敏感患者血清做了抗体检测。结果表明,首次移植前血清抗体阳性率为20.6%,再次移植前血清抗体阳性率75%。72份高敏感患者血清无论在4℃或在37℃均对B淋巴细胞反应,而对T淋巴细胞反应则少。因排斥而切除移植肾的透析患者其抗B淋巴细胞毒抗体高于输血和妊娠所致的淋巴细胞毒抗体。认为系统地了解肾移植受者的抗体水平,对移植肾的存活与进一步提高移植肾的存活率具有一定的意义。
Antibodies were detected in 459 serum samples from random dialysis patients before kidney transplantation, and 72 of them were tested for antibody against sera from patients with hypersensitivity to lymphocytes. The results showed that the positive rate of serum antibody before first transplantation was 20.6%, and the positive rate of serum antibody before re-transplantation was 75%. Seventy-two high-sensitive sera reacted to B lymphocytes at 4 ° C or 37 ° C with less response to T lymphocytes. Dialysis patients who have had transplant rejection due to rejection have a higher anti-B lymphocyte antibody than lymphocyte antibodies due to blood transfusions and pregnancies. It is of great significance to know the antibody level of kidney transplant recipients systematically to the survival of transplanted kidneys and the survival rate of transplanted kidneys.