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作者用戍巴比妥钠、氯胺酮和肌肉松弛剂使12只重350～400克的豚鼠麻醉,通过气管切开用人工呼吸器保持呼吸频率在20次/分左右,并用加热器使其体温保持在38℃上下。然后静脉缓慢注入(持续5分钟)40%甘油生理盐水溶液(不发生溶血:剂量2.4ml/kg),并在注射前、注射期间和注射后测量耳蜗内氧分压、耳蜗内电位以及由70分贝、4千赫哨音所激发的耳蜗微音效应,还检查了颈动脉血压。全部资料均用电子计算机记录,并经统计学处理。结果,发现注药后耳蜗内电位和耳蜗微音效应改变很小。而注药开始后血压立即下降,并持续到注射结束时,然后有上升趋势,经短时升高后于30分钟左右便恢复到近乎
The authors anesthetized 12 guinea pigs weighing 350-400 g with sodium pentobarbital, ketamine, and muscle relaxants, keeping the respiratory rate at about 20 beats / min by a tracheostomy with a respirator and holding the body temperature with a heater Up and down at 38 ℃. The vein was then slowly infused (for 5 minutes) in 40% glycerol saline (no hemolysis: 2.4 ml / kg dose) and the cochlear oxygen partial pressure, intracochlear potentials, Decibel, 4 kHz whistle-inspired cochlear micro-tone effect, but also check the carotid artery blood pressure. All data are recorded by electronic computer and processed by statistics. As a result, it was found that there was little change in the intracochlear potential and cochlear micro-tone effect after injection. The injection of blood pressure immediately after the start and continued until the end of injection, and then there is an upward trend, after a short rise in 30 minutes or so will return to almost