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目的探讨慢性鼻-鼻窦炎病人钩突内外侧面粘膜腺体的组织病理学差异。方法对接受鼻内镜手术慢性鼻-鼻窦炎16个病人20侧钩突的内外侧面粘膜通过HE染色、阿利辛蓝-过碘酸-雪夫(AB-PAS)特染、光镜下观察二者组织病理学的不同。结果慢性鼻-鼻窦炎钩突内侧面粘膜固有层中浆液腺面积明显少于外侧面;内侧面粘膜固有层中粘液腺面积明显多于外侧面。结论慢性鼻-鼻窦炎病人鼻腔粘膜和鼻窦粘膜的组织病理学改变是不同的。
Objective To investigate the histopathological differences between the medial and lateral mucosal glands of the patients with chronic rhinosinusitis. Methods The inner and outer mucosa of 20 patients with chronic rhinosinusitis who underwent nasal endoscopic sinus surgery were examined by HE stain, AB-PAS staining and light microscopy Histopathological differences. Results The area of serous gland in the inner lamina propria of chronic rhinosinusitis was significantly less than the lateral surface of the lamina propria. The area of mucous gland in the lamina propria of medial side was significantly more than that of the lateral side. Conclusion The histopathological changes of nasal mucosa and sinus mucosa in patients with chronic rhinosinusitis are different.