论文部分内容阅读
目的了解甘肃省2009年不同时期一般人群、甲型H1N1流行性感冒(甲流)康复者、疫苗接种者三类人群的甲流抗体水平。方法采用血凝抑制(Hemagglutination Inhibition,HI)试验检测HI抗体,≥1:40为阳性。结果 2009年8月底、11月底,甘肃省城市人群甲流抗体阳性率分别为3.64%(11/302)和10.45%(44/421)。2009年接种甲流疫苗后30d抗体阳性率46.13%(131/284),几何平均滴度(Geometric Mean Titer,GMT)为1:21.31。实验室确诊病例发病10～15d血清HI抗体阳性率为87.04%(47/54),15d后抗体阳性率为96.40%(134/139);GMT为1:139.4。结论甘肃省甲流首先在学生中形成爆发,目前已经扩散到不同年龄人群,人群甲流抗体水平仍很低,疫苗接种率低(6.65%),人群普遍对甲流缺乏免疫力,甲流将继续在人群中流行。加强甲流疫苗接种、做好重症病例的救治,依然是当前预防控制的重点。
Objective To understand the level of antibody against influenza A (H1N1) in three groups of general population, type A H1N1 influenza (H1N1) and vaccinated persons in different periods in Gansu Province in 2009. Methods HI antibody was detected by Hemagglutination Inhibition (HI) test, and ≥1: 40 was positive. Results At the end of August 2009 and the end of November, the positive rates of influenza A antibody in urban population of Gansu Province were 3.64% (11/302) and 10.45% (44/421) respectively. The positive rate of antibody was 46.13% (131/284) after 30 days of 2009 vaccination, and the geometric mean titer (GMT) was 1: 21.31. The positive rate of serum HI antibody in laboratory confirmed cases was 87.04% (47/54) after 10-15 days, and the positive rate was 96.40% (134/139) after 15 days. The GMT was 1: 139.4. Conclusions A stream of Gansu Province first broke out among the students and has now spread to different age groups. The antibody level in population is still low, the vaccination rate is low (6.65%), the population is generally lack of immunity to the H1N1 influenza, Continue to pop in the crowd. To strengthen the flow of a vaccination, do a good job in the treatment of severe cases, is still the focus of current prevention and control.