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本文报告异丁羟苯丙酸(布洛芬,Ibuprofen)的抗蛋白尿效果。本组共23例,男12例,女11例,年龄17~58岁。慢性肾炎22例(急性肾炎后症状持续一年以上而成慢性者4例,原发性慢性肾炎18例),另1例系肾病综合征;其中3例有肾功能减退。异丁羟苯丙酸使用剂量为300~1200毫克/日,用药14~55天。疗效判断标准:尿蛋白转为阴性为显效,减少到用药前的25%以下为有效,减少到25~70%为微效,在原来的70%以上为无效。结果:(1)抗蛋白尿效果与用药剂量有密切关系,计1200毫克/日的8例,900毫克/日的6例,600毫
This article reports the anti-proteinuric efficacy of ibuprofen (ibuprofen). The group of 23 cases, 12 males and 11 females, aged 17 to 58 years. 22 cases of chronic nephritis (chronic nephritis symptoms lasting more than one year and chronic in 4 cases, 18 cases of primary chronic nephritis), another case of nephrotic syndrome; of which 3 cases of renal dysfunction. Isobutyl phenylpropanoic acid dose of 300 ~ 1200 mg / day, medication for 14 to 55 days. Efficacy criteria: urinary protein to negative for the marked effect, reduced to less than 25% before treatment is effective, reduced to 25 to 70% for the micro-effect, more than 70% of the original is invalid. Results: (1) The anti-proteinuria effect is closely related to the dose of the medicine, including 8 cases of 1200 mg / day, 6 cases of 900 mg / day and 600 milligrams