原发性巨球蛋白血症是一种单株峰IgM增多,以浆细胞样淋巴细胞增殖为特征的疾病,亦称Waldenstr(?)m巨球蛋白血症。发病年龄多在50岁以上;男性略多于女性。如继发于某些支气管癌、淋巴瘤、系统性红斑狼疮,类风湿性关节炎、慢性活动性肝炎等疾病,则称为继发性巨球蛋白血症。该病的肾脏受累并不少见,如出现大量蛋白尿 Primary macroglobulinemia is a disease characterized by an increase in IgM per plant peak, characterized by plasmacytoid lymphocyte proliferation, also known as Waldenstr (?) M macroglobulinemia. Age more than 50 years of age; men slightly more than women. Such as secondary to some bronchial cancer, lymphoma, systemic lupus erythematosus, rheumatoid arthritis, chronic active hepatitis and other diseases, is called secondary macroglobulinemia. Kidney involvement of the disease is not uncommon, such as a large number of proteinuria