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Ｂｃｌ－２基因是一个阻遏细胞凋亡基因，其编码的Ｂｃｌ－２蛋白能阻止细胞凋亡，该蛋白的异常表达与恶性肿瘤发生发展及预后有密切关系［１，２］。Ｐ５３为肿瘤抑制基因，该基因突变和其编码的Ｐ５３蛋白过度表达与恶性肿瘤的生物学行为和预后有较密切的关系［３，４］...
Bcl-2 gene is a repressor of apoptosis gene, and its encoded Bcl-2 protein can prevent apoptosis. The abnormal expression of this protein is closely related to the development and prognosis of malignant tumors [1, 2]. P53 is a tumor suppressor gene. The mutation and the overexpression of the encoded P53 protein have a close relationship with the biological behavior and prognosis of malignant tumors [3,4]...