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通过对克山病病区和非病区儿童红细胞和发硒含量的测定，以及血小板的电镜观察，发现处于低硒状态的病区儿童血小板超微结构明显异常：盘状血小板数减少，变形和团聚血小板所占比例显著增高；拥挤成团的血小板膜融合或紧密联接；细胞器呈非特异性溶解状，α－颗粒和致密颗粒电子密度均降低；α－颗粒数显著减少，致密颗粒数无明显变化。结果表明，克山病病区低硒儿童血小板处于激活状态。
Through the determination of erythrocytes and selenium in Keshan disease and non-ward children and the electron microscope observation of platelets, it was found that the ultrastructural changes of platelets in children with low selenium status were obviously abnormal: the number of platelet platelets decreased, the deformation and The proportion of aggregated platelets was significantly increased; crowded platelet membrane fusion or tight adhesion; organelles were nonspecific dissolution, α-particles and dense particles were reduced electron density; α-particles significantly reduced the number of dense particles without significant changes . The results showed that platelets in the selenium-deficient children in Keshan disease were active.