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复合氨基酸18(AAC18)是一种新型复合氨基酸输液剂,实验证明对家兔急性致死性出血有明显保护作用(P<0.01)。静脉给低蛋白血症家兔AAC18-3(20ml/kg·d)5d,可显著升高血清总蛋白(2.0+0.7g/L)和白蛋白,(1.0+0.1g/L)(P<0.05),伤口愈合时间平均缩短1.5d,静脉给蛋白质营养不良大鼠AAC18-3或AAC18-10(20ml/kg·d)21d,可明显升高大鼠血清总蛋白和白蛋白(P<0.01),后者还能明显增加大鼠体重。各项试验分别与日本同类产品(Mo-N或MO-SN)平行对照,结果差异均无显著性意义。
Compound Amino Acid 18 (AAC18) is a new compound amino acid infusion agent, which has been proved to have a significant protective effect on acute lethal hemorrhage in rabbits (P <0.01). Intravenous administration of AAC18-3 (20ml / kg · d) for 5 days in rabbits with hypoproteinemia increased serum total protein (2.0 ± 0.7g / L) and albumin, (1.0 ± 0.1g / L) 0.05). The mean wound healing time was shortened 1.5d. Serum total protein and albumin of rats with protein malnutrition were significantly increased by intravenous administration of AAC18-3 or AAC18-10 (20ml / kg · d) for 21d (P <0.01) , The latter can also significantly increase the body weight of rats. The tests were parallel with similar products in Japan (Mo-N or MO-SN), the results were no significant difference.