扭转痉挛又名扭转性肌张力障碍或豆状核性肌张力障碍。临床上以肌张力障碍和四肢、躯干甚至全身的剧烈而不随意的扭转为特征。既往临床上常予给镇静剂、肌肉松弛剂、抗震颤麻痹药等,疗效轻微短暂,毒副作用大。我科自1996年5月应用A型肉毒毒素多点肌肉注射治疗扭转痉挛9例,其中原发性扭转痉挛5例,肝豆状核变性所致扭转痉挛4例,并随访8～15个月,发现疗效较好,现报告如下。 Torsion spasm, also known as dystonia or bean-like dystonia. Clinically, it is characterized by intense and involuntary twisting of dystonia and limbs, trunk and even the whole body. Previously often given to the clinical sedatives, muscle relaxants, anti-paralysis paralysis and other drugs, the efficacy of a slight transient, side effects. Our department from May 1996 botulinum toxin type A multi-point intramuscular injection treatment of torsion spasm in 9 cases, including 5 cases of primary torsion spasm, hepatic degeneration caused by liver spasm in 4 cases, and followed up 8 to 15 Month, found that better efficacy, are as follows.