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目的探讨对肝硬化合并上消化道出血患者选择奥曲肽联合泮托拉唑治疗的临床效果。方法 52例肝硬化合并上消化道出血患者作为研究对象,采用抽签的形式分为观察组与对照组,每组26例。观察组给予奥曲肽联合泮托拉唑治疗;对照组给予泮托拉唑治疗。观察对比两组的治疗效果。结果经治疗,观察组显效14例、有效11例、无效1例,总有效25例,总有效率为96.15%;对照组显效5例、有效12例、无效9例,总有效17例,总有效率为65.38%。观察组治疗总有效率高于对照组,差异具有统计学意义(P<0.05)。结论对于肝硬化合并上消化道出血患者,针对疾病情况进行分析后,合理选择奥曲肽联合泮托拉唑进行治疗,临床效果显著,值得临床推广。
Objective To investigate the clinical effects of octreotide combined with pantoprazole in patients with cirrhosis and upper gastrointestinal bleeding. Methods Fifty-two patients with cirrhosis and upper gastrointestinal hemorrhage were divided into observation group and control group by lottery, with each group having 26 cases. The observation group was treated with octreotide plus pantoprazole; the control group was given pantoprazole. Observed and compared the treatment effect of two groups. Results After treatment, the observation group was significantly improved in 14 cases, effective in 11 cases, ineffective in 1 case, total effective in 25 cases, the total effective rate was 96.15%; the control group markedly effective in 5 cases, effective in 12 cases, ineffective in 9 cases, total effective in 17 cases, total effective The effective rate is 65.38%. The total effective rate of observation group was higher than that of control group, the difference was statistically significant (P <0.05). Conclusion For patients with cirrhosis and upper gastrointestinal bleeding, the analysis of the disease situation, the rational choice of octreotide combined with pantoprazole for treatment, the clinical effect is significant, worthy of clinical promotion.