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5～15岁的HBV易感儿童,按0、1、6月程序接种10μg×3乙型肝炎血源疫苗(北京生研所批号8615-1A、8722-2)。接种后1～2年他们的抗-HBs阳转率为～92％,无一例HBsAg阳转;未接种疫苗的对照组儿童,抗-HBs阳转率仅2.08％～2.60％,HBsAg阳转率分别为3.23％和2.08％。流行病学保护效果良好。易感少年儿童接种乙型肝炎血源疫苗将加快控制乙型肝炎的进程。
HBV-susceptible children aged 5-15 years old were vaccinated with 10 μg × 3 Hepatitis B vaccine (Dayang Research Institute No. 8615-1A, 8722-2) according to the procedures of 0, 1, and 6 months. Their anti-HBs positive rate was ~ 92% 1 to 2 years after inoculation, and none of HBsAg positive mothers in the unvaccinated control group had anti-HBs positive rate of only 2.08% -2.60%. The HBsAg positive rate Respectively 3.23% and 2.08%. Epidemiological protection works well. Susceptible children vaccination of hepatitis B blood vaccine will speed up the process of control of hepatitis B.